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KMID : 1123920150290060443
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Korean Journal of Oriental Physiology and Pathology
2015 Volume.29 No. 6 p.443 ~ p.450
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Status of Construction of TCM Network Pharmacology Databases and Potential Application of TCMSP to Korean Traditional Medicine - mainly with Sasang-related Herbs
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Hwang Sang-Moon
Beck Jong-Min
Suh Su-Yeon
Kwon Young-Kyu
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Abstract
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The purpose of this study was is to understand how the network pharmacology databases of traditional medicine in China are established and provide suggestion for successful implementation in Traditional Korean Medicine. We searched for network-pharmacology-related TCM Databases provided on the internet, and analysed their contents. Then, we compared herbs related to Sasang with herbs of the TCM Databases. We chose 8 network-pharmacology-related TCM Databases. They shared information about compounds, herbs, formulae, drugs, targets and diseases, and provided interaction networks between these components. In comparison with herbs related to Sasang, TCMSP Database did not have information about 99 herbs in total, and 25 herbs included in major Sasang formulae. The implications and recommendations for Traditional Korean Medicine researches were discussed. Based on the results of this primary study, more related studies should be carried out in the future.
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KEYWORD
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Network pharmacology, Systems biology, TCMSP, TCM, Traditional Korean medicine, Sasang Medicine
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